When it comes to antidepressant medications, most are actually known for a risk of causing people to put on quite a number of extra pounds. However, the Bupropion antidepressant is proving to be notably different from others within its category, according to a recent publication in the Journal of Clinical Medicine, which contained a new retrospective cohort study.
According to the study leader, David Arterburn, MD, from the Group Health Research Institute in Seattle, Washington, while “all other antidepressants” currently have a link to weight gain in varying degrees of severity, in the case of the Bupropion antidepressant, the opposite tends to be the case. Over a period of two years, many people using this medication seem to be more inclined to decrease their body fat levels than to increase them.
The Bupropion antidepressant research indicated that because of the difference in side effects that it can cause, it may be the “best initial choice” for this type of medication for most Americans who are both depressed and either obese or overweight, said Arterburn.
That said, it should be pointed out that it wasn’t all users of this medication who were able to experience a loss of weight throughout the time they were using it. Over the period of two years, those who didn’t smoke were able to shed weight while those who smoked did not experience this same effect. This was particularly interesting as smoking cessation is frequently associated with weight gain, which indicates that if Bupropion were prescribed to patients who were also attempting to quit smoking, it could help to counteract potential weight gain.
Other drugs that were considered within the retrospective cohort study examined electronic health records of patients who were adults and who were using second generation antidepressant monotherapy treatments between the years 2005 and 2009. As a reference, fluoxetine was used, and the study itself included bupropion as well as paroxetine, citalopram, sertraline, trazodone, mirtazapine, venlafaxine and duloxetine.
Of course, even though Bupropion is associated with certain weight loss benefits, that doesn’t mean that it can necessarily be used specifically for weight loss when symptoms of depression or other mental health conditions for which this drug is prescribed are not present. This is a serious drug that impacts the chemicals of the brain. For safe and effective weight loss without the use of an antidepressant, many people look to Phentramin-D, which is known for its appetite suppressant, fat burning and energy boosting ingredients.